4JWN
Ternary complex of D256A mutant of DNA Polymerase Beta
Summary for 4JWN
Entry DOI | 10.2210/pdb4jwn/pdb |
Related | 4JWM |
Descriptor | DNA polymerase beta, DNA (5'-D(*CP*CP*GP*AP*CP*AP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3'), ... (9 entities in total) |
Functional Keywords | nucleotidyl transfer, dntp, non-hydrolyzable analog, transferase-dna complex, transferase/dna |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 48327.12 |
Authors | Batra, V.K.,Perera, L.,Ping, L.,Shock, D.D.,Beard, W.A.,Pedersen, L.C.,Pedersen, L.G.,Wilson, S.H. (deposition date: 2013-03-27, release date: 2013-06-26, Last modification date: 2023-09-20) |
Primary citation | Batra, V.K.,Perera, L.,Lin, P.,Shock, D.D.,Beard, W.A.,Pedersen, L.C.,Pedersen, L.G.,Wilson, S.H. Amino Acid Substitution in the Active Site of DNA Polymerase beta Explains the Energy Barrier of the Nucleotidyl Transfer Reaction. J.Am.Chem.Soc., 135:8078-8088, 2013 Cited by PubMed: 23647366DOI: 10.1021/ja403842j PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.39 Å) |
Structure validation
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