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4JTK

Crystal structure of R117Q mutant of 3-deoxy-D-manno-octulosonate 8-phosphate synthase (KDO8PS) from Neisseria meningitidis

Summary for 4JTK
Entry DOI10.2210/pdb4jtk/pdb
Related4JTE 4JTF 4JTG 4JTH 4JTI 4JTJ 4JTL
Descriptor2-dehydro-3-deoxyphosphooctonate aldolase, CHLORIDE ION, SODIUM ION, ... (4 entities in total)
Functional Keywordsmanno-octulosonate, synthase, lipopolysaccharide, kdop, kdo8 kdops, kdo8ps, tim barrel, transferase, lipopolysaccharide biosynthesis
Biological sourceNeisseria meningitidis
Cellular locationCytoplasm (By similarity): Q9JZ55
Total number of polymer chains4
Total formula weight122125.84
Authors
Allison, T.M.,Cochrane, F.C.,Jameson, G.B.,Parker, E.J. (deposition date: 2013-03-23, release date: 2013-06-26, Last modification date: 2023-09-20)
Primary citationAllison, T.M.,Cochrane, F.C.,Jameson, G.B.,Parker, E.J.
Examining the Role of Intersubunit Contacts in Catalysis by 3-Deoxy-d-manno-octulosonate 8-Phosphate Synthase.
Biochemistry, 52:4676-4686, 2013
Cited by
PubMed: 23746359
DOI: 10.1021/bi400521f
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.86 Å)
Structure validation

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