4JPF

Structure of wild type Pseudomonas aeruginosa FabF (KASII) in Complex with ligand

Summary for 4JPF

Entry DOI	10.2210/pdb4jpf/pdb
Related	4b7v 4jb6
Descriptor	3-oxoacyl-[acyl-carrier-protein] synthase 2, 3-(benzoylamino)-2-hydroxybenzoic acid, MAGNESIUM ION, ... (5 entities in total)
Functional Keywords	fatty acid biosynthesis, fabf, kasii, transferase
Biological source	Pseudomonas aeruginosa
Total number of polymer chains	1
Total formula weight	46423.39
Authors	Baum, B.,Brenk, R.,Jaenicke, E. (deposition date: 2013-03-19, release date: 2014-04-02, Last modification date: 2023-09-20)
Primary citation	Baum, B.,Lecker, L.S.,Zoltner, M.,Jaenicke, E.,Schnell, R.,Hunter, W.N.,Brenk, R. Structures of Pseudomonas aeruginosa beta-ketoacyl-(acyl-carrier-protein) synthase II (FabF) and a C164Q mutant provide templates for antibacterial drug discovery and identify a buried potassium ion and a ligand-binding site that is an artefact of the crystal form. Acta Crystallogr F Struct Biol Commun, 71:1020-1026, 2015 Cited by PubMed: 26249693 DOI: 10.1107/S2053230X15010614 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.67 Å)

Structure validation