4JH9

Crystal Structure of FosB from Bacillus cereus with Maganese and Potential BSH-Fosfomycin Product

Summary for 4JH9

Entry DOI	10.2210/pdb4jh9/pdb
Related	4JH1 4JH2 4JH3 4JH4 4JH5 4JH6 4JH7 4JH8
Descriptor	Metallothiol transferase FosB, MANGANESE (II) ION, (2R)-2-azanyl-3-[(1R,2S)-2-oxidanyl-1-phosphono-propyl]sulfanyl-propanoic acid, ... (4 entities in total)
Functional Keywords	bacillithiol-s-transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological source	Bacillus cereus
Cellular location	Cytoplasm : Q739M9
Total number of polymer chains	2
Total formula weight	33605.28
Authors	Thompson, M.K.,Harp, J.,Keithly, M.E.,Jagessar, K.,Cook, P.D.,Armstrong, R.N. (deposition date: 2013-03-04, release date: 2013-10-02, Last modification date: 2024-02-28)
Primary citation	Thompson, M.K.,Keithly, M.E.,Harp, J.,Cook, P.D.,Jagessar, K.L.,Sulikowski, G.A.,Armstrong, R.N. Structural and Chemical Aspects of Resistance to the Antibiotic Fosfomycin Conferred by FosB from Bacillus cereus. Biochemistry, 52:7350-7362, 2013 Cited by PubMed: 24004181 DOI: 10.1021/bi4009648 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.77 Å)

Structure validation