4J6D

The 2.4 A crystal structure of CYP154C5 from Nocardia farcinica in complex with testosterone

Summary for 4J6D

• Entry DOI: 10.2210/pdb4j6d/pdb
• Related: 4J6B 4J6C 4JBT
• Descriptor: Cytochrome P450 monooxygenase, PROTOPORPHYRIN IX CONTAINING FE, MAGNESIUM ION, ... (7 entities in total)
• Functional Keywords: cytochrom p450, steroid hydroxylating monooxygenase, steroid binding, oxidoreductase-substrate complex, oxidoreductase/substrate
• Biological source: Nocardia farcinica
• Total number of polymer chains: 2
• Total formula weight: 92874.35

Authors

Herzog, K.,Hoffmann, K.M. (deposition date: 2013-02-11, release date: 2014-03-05, Last modification date: 2023-09-20)

• Primary citation: Herzog, K.,Bracco, P.,Onoda, A.,Hayashi, T.,Hoffmann, K.,Schallmey, A.; Enzyme-substrate complex structures of CYP154C5 shed light on its mode of highly selective steroid hydroxylation.; Acta Crystallogr.,Sect.D, 70:2875-2889, 2014; PubMed: 25372679; DOI: 10.1107/S1399004714019129

Experimental method

X-RAY DIFFRACTION (2.4 Å)