4J19
Structure of a novel telomere repeat binding protein bound to DNA
Summary for 4J19
Entry DOI | 10.2210/pdb4j19/pdb |
Descriptor | Homeobox-containing protein 1, DNA (5'-D(*CP*TP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*G)-3'), DNA (5'-D(*TP*CP*TP*AP*AP*CP*CP*CP*TP*AP*AP*CP*CP*CP*TP*AP*AP*CP*A)-3'), ... (5 entities in total) |
Functional Keywords | telomere repeat binding, telomeric dna, transcription-dna complex, transcription/dna |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus . Isoform 5: Nucleus : Q6NT76 |
Total number of polymer chains | 4 |
Total formula weight | 37865.87 |
Authors | Kappei, D.,Butter, F.,Benda, C.,Scheibe, M.,Draskovic, I.,Stevense, M.,Lopes Novo, C.,Basquin, C.,Krastev, D.B.,Kittler, R.,Jessberger, R.,Londono-Vallejo, A.J.,Mann, M.,Buchholz, F. (deposition date: 2013-02-01, release date: 2013-05-29, Last modification date: 2023-09-20) |
Primary citation | Kappei, D.,Butter, F.,Benda, C.,Scheibe, M.,Draskovic, I.,Stevense, M.,Novo, C.L.,Basquin, C.,Araki, M.,Araki, K.,Krastev, D.B.,Kittler, R.,Jessberger, R.,Londono-Vallejo, J.A.,Mann, M.,Buchholz, F. HOT1 is a mammalian direct telomere repeat-binding protein contributing to telomerase recruitment. Embo J., 32:1681-1701, 2013 Cited by PubMed: 23685356DOI: 10.1038/emboj.2013.105 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
Download full validation report