4IHD
Crystal Structure of Uncleaved ThnT T282C, derivatized at the active site with EtHg
Summary for 4IHD
Entry DOI | 10.2210/pdb4ihd/pdb |
Related | 3S3U 3TM1 3TM2 4IHE |
Descriptor | ThnT protein, ETHYL MERCURY ION (3 entities in total) |
Functional Keywords | dom-fold, clan pe, family p1, autoproteolysis, pantetheine hydrolase, thienamycin biosynthesis, ethylmercury derivatization of c282, hydrolase |
Biological source | Streptomyces cattleya |
Total number of polymer chains | 2 |
Total formula weight | 83207.54 |
Authors | Buller, A.R.,Schildbach, J.F.,Townsend, C.A. (deposition date: 2012-12-18, release date: 2014-08-13, Last modification date: 2023-09-20) |
Primary citation | Buller, A.R.,Freeman, M.F.,Schildbach, J.F.,Townsend, C.A. Exploring the Role of Conformational Heterogeneity in cis-Autoproteolytic Activation of ThnT. Biochemistry, 53:4273-4281, 2014 Cited by PubMed: 24933323DOI: 10.1021/bi500385d PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.65 Å) |
Structure validation
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