4IHB

X-RAY STRUCTURE OF THE canonical C2A DOMAIN FROM HUMAN DYSFERLIN

Summary for 4IHB

Entry DOI	10.2210/pdb4ihb/pdb
Related	2DMH 3L9B 4IQH
Descriptor	Dysferlin, FORMIC ACID, CALCIUM ION, ... (4 entities in total)
Functional Keywords	beta sandwich, type ii c2 domain, muscular dystrophy, membrane protein, membrane repair, plasma membrane
Biological source	Homo sapiens (human)
Cellular location	Cell membrane, sarcolemma; Single-pass type II membrane protein: O75923
Total number of polymer chains	6
Total formula weight	89216.40
Authors	Sutton, R.B.,Fuson, K.L. (deposition date: 2012-12-18, release date: 2013-12-18, Last modification date: 2023-09-20)
Primary citation	Fuson, K.,Rice, A.,Mahling, R.,Snow, A.,Nayak, K.,Shanbhogue, P.,Meyer, A.G.,Redpath, G.M.,Hinderliter, A.,Cooper, S.T.,Sutton, R.B. Alternate Splicing of Dysferlin C2A Confers Ca(2+)-Dependent and Ca(2+)-Independent Binding for Membrane Repair. Structure, 22:104-115, 2014 Cited by PubMed: 24239457 DOI: 10.1016/j.str.2013.10.001 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.044 Å)

Structure validation