4IHB
X-RAY STRUCTURE OF THE canonical C2A DOMAIN FROM HUMAN DYSFERLIN
Summary for 4IHB
Entry DOI | 10.2210/pdb4ihb/pdb |
Related | 2DMH 3L9B 4IQH |
Descriptor | Dysferlin, FORMIC ACID, CALCIUM ION, ... (4 entities in total) |
Functional Keywords | beta sandwich, type ii c2 domain, muscular dystrophy, membrane protein, membrane repair, plasma membrane |
Biological source | Homo sapiens (human) |
Cellular location | Cell membrane, sarcolemma; Single-pass type II membrane protein: O75923 |
Total number of polymer chains | 6 |
Total formula weight | 89216.40 |
Authors | Sutton, R.B.,Fuson, K.L. (deposition date: 2012-12-18, release date: 2013-12-18, Last modification date: 2023-09-20) |
Primary citation | Fuson, K.,Rice, A.,Mahling, R.,Snow, A.,Nayak, K.,Shanbhogue, P.,Meyer, A.G.,Redpath, G.M.,Hinderliter, A.,Cooper, S.T.,Sutton, R.B. Alternate Splicing of Dysferlin C2A Confers Ca(2+)-Dependent and Ca(2+)-Independent Binding for Membrane Repair. Structure, 22:104-115, 2014 Cited by PubMed: 24239457DOI: 10.1016/j.str.2013.10.001 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.044 Å) |
Structure validation
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