4IFN
Crystal Structures of apo Keap1, Keap1-peptide, and Keap1-compound complexes
Summary for 4IFN
Entry DOI | 10.2210/pdb4ifn/pdb |
Related | 4IFJ 4IFL |
Descriptor | kelch-like ECH-associated protein 1, (1R,2R)-2-{[(1S)-1-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]-3,4-dihydroisoquinolin-2(1H)-yl]carbonyl}cyclohexanecarboxylic acid (3 entities in total) |
Functional Keywords | protein binding, transcription |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: Q14145 |
Total number of polymer chains | 1 |
Total formula weight | 32275.02 |
Authors | Pan, H.,Lin, M.,Yang, Y.,Callaway, K.,Baker, J.,Diep, L.,Yan, J.,Tanaka, K.,Zhu, Y.L.,Konradi, A.W.,Jobling, M.,Tam, D.,Ren, Z.,Cheung, H.,Bova, M.,Riley, B.E.,Yao, N.,Artis, D.R. (deposition date: 2012-12-14, release date: 2013-12-18) |
Primary citation | Pan, H.,Lin, M.,Yang, Y.,Callaway, K.,Baker, J.,Diep, L.,Yan, J.,Tanaka, K.,Zhu, Y.L.,Konradi, A.W.,Jobling, M.,Tam, D.,Ren, Z.,Cheung, H.,Bova, M.,Riley, B.E.,Yao, N.,Artis, D.R. Crystal Structures of apo Keap1, Keap1-peptide, and Keap1-compound complexes Acta Crystallogr.,Sect.D, |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
Download full validation report