4IC2

Crystal structure of the XIAP RING domain

Summary for 4IC2

Entry DOI	10.2210/pdb4ic2/pdb
Related	4IC3
Descriptor	E3 ubiquitin-protein ligase XIAP, ZINC ION, NICKEL (II) ION, ... (4 entities in total)
Functional Keywords	ring domain, zinc-finger, e3 ligase, ligase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: P98170
Total number of polymer chains	2
Total formula weight	17110.33
Authors	Linke, K.,Nakatani, Y.,Day, C.L. (deposition date: 2012-12-09, release date: 2012-12-19, Last modification date: 2023-11-08)
Primary citation	Nakatani, Y.,Kleffmann, T.,Linke, K.,Condon, S.M.,Hinds, M.G.,Day, C.L. Regulation of ubiquitin transfer by XIAP, a dimeric RING E3 ligase Biochem.J., 450:629-638, 2013 Cited by PubMed: 23259674 DOI: 10.1042/BJ20121702 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation