4I8V
Human Cytochrome P450 1A1 in complex with alpha-naphthoflavone
Summary for 4I8V
Entry DOI | 10.2210/pdb4i8v/pdb |
Descriptor | Cytochrome P450 1A1, PROTOPORPHYRIN IX CONTAINING FE, 2-PHENYL-4H-BENZO[H]CHROMEN-4-ONE, ... (5 entities in total) |
Functional Keywords | monooxygenase, cytochrome p450, p450, cyp1a1, p450 1a1, heme, oxidoreductase, aryl hydrocarbon hydroxylase |
Biological source | Homo sapiens (human) |
Cellular location | Endoplasmic reticulum membrane; Peripheral membrane protein: P04798 |
Total number of polymer chains | 4 |
Total formula weight | 227517.78 |
Authors | Walsh, A.A.,Scott, E.E. (deposition date: 2012-12-04, release date: 2013-02-27, Last modification date: 2023-09-20) |
Primary citation | Walsh, A.A.,Szklarz, G.D.,Scott, E.E. Human Cytochrome P450 1A1 Structure and Utility in Understanding Drug and Xenobiotic Metabolism. J.Biol.Chem., 288:12932-12943, 2013 Cited by PubMed: 23508959DOI: 10.1074/jbc.M113.452953 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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