4I51

Methyltransferase domain of HUMAN EUCHROMATIC HISTONE METHYLTRANSFERASE 1, mutant Y1211A

Replaces:  4H4H

Summary for 4I51

• Entry DOI: 10.2210/pdb4i51/pdb
• Descriptor: Histone-lysine N-methyltransferase EHMT1, H3K9 NE-ALLYL PEPTIDE, UNKNOWN PEPTIDE, ... (8 entities in total)
• Functional Keywords: ne-allyl peptide, structural genomics consortium, transferase-peptide complex, sgc, transferase/peptide
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus: Q9H9B1
• Total number of polymer chains: 5
• Total formula weight: 70383.53

Authors

Dong, A.,Zeng, H.,Walker, J.R.,Islam, K.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.M.,Lou, M.,Min, J.,Wu, H.,Structural Genomics Consortium (SGC) (deposition date: 2012-11-28, release date: 2012-12-19, Last modification date: 2023-12-06)

• Primary citation: Islam, K.,Chen, Y.,Wu, H.,Bothwell, I.R.,Blum, G.J.,Zeng, H.,Dong, A.,Zheng, W.,Min, J.,Deng, H.,Luo, M.; Defining efficient enzyme-cofactor pairs for bioorthogonal profiling of protein methylation.; Proc.Natl.Acad.Sci.USA, 110:16778-16783, 2013; PubMed: 24082136; DOI: 10.1073/pnas.1216365110

Experimental method

X-RAY DIFFRACTION (1.9 Å)