4I2S
Crystal structure of rabbit ryanodine receptor 1 (residues 1-536) disease mutant I404M
Summary for 4I2S
| Entry DOI | 10.2210/pdb4i2s/pdb |
| Related | 2XOA 4I0Y 4I1E 4I37 4I3N 4I6I 4I7I 4I8M 4I96 |
| Descriptor | Ryanodine receptor 1, GLYCEROL (3 entities in total) |
| Functional Keywords | calcium channel, sr/er membrane, metal transport |
| Biological source | Oryctolagus cuniculus (rabbit) |
| Cellular location | Sarcoplasmic reticulum membrane; Multi-pass membrane protein: P11716 |
| Total number of polymer chains | 1 |
| Total formula weight | 59586.52 |
| Authors | Kimlicka, L.,Van Petegem, F. (deposition date: 2012-11-22, release date: 2013-02-20, Last modification date: 2023-09-20) |
| Primary citation | Kimlicka, L.,Lau, K.,Tung, C.C.,Van Petegem, F. Disease mutations in the ryanodine receptor N-terminal region couple to a mobile intersubunit interface. Nat Commun, 4:1506-1506, 2013 Cited by PubMed: 23422674DOI: 10.1038/ncomms2501 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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