4I1O
Crystal structure of the Legionella pneumophila GAP domain of LepB in complex with Rab1b bound to GDP and BeF3
Summary for 4I1O
Entry DOI | 10.2210/pdb4i1o/pdb |
Related | 4I1M |
Descriptor | Ras-related protein Rab-1B, LepB, MAGNESIUM ION, ... (7 entities in total) |
Functional Keywords | gap, rabgap, hydrolase activator, rab1b, lpg2490, gtpase-activating proteins, hydrolysis, rab1 hydrolase, gtp hydrolase, protein transport-hydrolase complex, protein transport/hydrolase |
Biological source | Homo sapiens (human) More |
Cellular location | Membrane; Lipid-anchor; Cytoplasmic side: Q9H0U4 |
Total number of polymer chains | 8 |
Total formula weight | 221227.36 |
Authors | Gazdag, E.M.,Streller, A.,Vetter, I.R.,Goody, R.S.,Itzen, A. (deposition date: 2012-11-21, release date: 2013-01-16, Last modification date: 2023-09-20) |
Primary citation | Mihai Gazdag, E.,Streller, A.,Haneburger, I.,Hilbi, H.,Vetter, I.R.,Goody, R.S.,Itzen, A. Mechanism of Rab1b deactivation by the Legionella pneumophila GAP LepB. Embo Rep., 14:199-205, 2013 Cited by PubMed: 23288104DOI: 10.1038/embor.2012.211 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.701 Å) |
Structure validation
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