4HZH
Structure of recombinant Gla-domainless prothrombin mutant S525A
Summary for 4HZH
Entry DOI | 10.2210/pdb4hzh/pdb |
Related | 3NXP 4HZQ |
Descriptor | Prothrombin, 2-acetamido-2-deoxy-beta-D-glucopyranose (2 entities in total) |
Functional Keywords | prothrombin, kringle, serine protease, coagulation, hydrolase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 121115.60 |
Authors | Pozzi, N.,Niu, W.,Gohara, D.W.,Chen, Z.,Di Cera, E. (deposition date: 2012-11-15, release date: 2013-06-26, Last modification date: 2023-09-20) |
Primary citation | Pozzi, N.,Chen, Z.,Gohara, D.W.,Niu, W.,Heyduk, T.,Di Cera, E. Crystal structure of prothrombin reveals conformational flexibility and mechanism of activation. J.Biol.Chem., 288:22734-22744, 2013 Cited by PubMed: 23775088DOI: 10.1074/jbc.M113.466946 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.3 Å) |
Structure validation
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