4HXY

PlmKR1-Ketoreductase from the first module of phoslactomycin biosynthesis in Streptomyces sp. HK803

Summary for 4HXY

Entry DOI	10.2210/pdb4hxy/pdb
Descriptor	Plm1, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 6-AMINOHEXANOIC ACID, ... (4 entities in total)
Functional Keywords	short chain dehydrogenase/reductase, ketoreductase, rossmann fold, oxidoreductase
Biological source	Streptomyces sp. HK803
Total number of polymer chains	2
Total formula weight	92701.95
Authors	Whicher, J.R.,Smith, J.L. (deposition date: 2012-11-12, release date: 2013-07-10, Last modification date: 2023-11-15)
Primary citation	Bonnett, S.A.,Whicher, J.R.,Papireddy, K.,Florova, G.,Smith, J.L.,Reynolds, K.A. Structural and Stereochemical Analysis of a Modular Polyketide Synthase Ketoreductase Domain Required for the Generation of a cis-Alkene. Chem.Biol., 20:772-783, 2013 Cited by PubMed: 23790488 DOI: 10.1016/j.chembiol.2013.04.014 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.68 Å)

Structure validation