4HXJ
Crystal structure of SH3:RGT complex
Summary for 4HXJ
Entry DOI | 10.2210/pdb4hxj/pdb |
Related | 1FMK |
Descriptor | Proto-oncogene tyrosine-protein kinase Src, C-terminal 3-mer peptide from Integrin beta-3 (3 entities in total) |
Functional Keywords | integrin beta-3, c-src kinase, sh3 domain, rgt, thrombosis, cell signaling, blood clotting, signaling protein |
Biological source | Homo sapiens (human) More |
Cellular location | Cell membrane: P12931 Cell membrane; Single-pass type I membrane protein: P05106 |
Total number of polymer chains | 3 |
Total formula weight | 13779.83 |
Authors | |
Primary citation | Xiao, R.,Xi, X.D.,Chen, Z.,Chen, S.J.,Meng, G. Structural framework of c-Src activation by integrin beta 3 Blood, 121:700-706, 2013 Cited by PubMed: 23169783DOI: 10.1182/blood-2012-07-440644 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
Download full validation report