4HUU
Crystal Structure of H2Db-NPM6I
Summary for 4HUU
Entry DOI | 10.2210/pdb4huu/pdb |
Related | 1hoc 3cpl 4HUV 4HUW 4HUX 4HV8 |
Descriptor | H-2 class I histocompatibility antigen, D-B alpha chain, Beta-2-microglobulin, NPM6I variant peptide, ... (5 entities in total) |
Functional Keywords | viral immunity, t cell, h2db, influenza, viral escape, immune system |
Biological source | Mus musculus (mouse) More |
Cellular location | Membrane; Single-pass type I membrane protein: P01899 Secreted: P01887 |
Total number of polymer chains | 6 |
Total formula weight | 90919.91 |
Authors | Gras, S.,Twist, K.A.,Rossjohn, J. (deposition date: 2012-11-04, release date: 2013-02-27, Last modification date: 2023-09-20) |
Primary citation | Valkenburg, S.A.,Gras, S.,Guillonneau, C.,Hatton, L.A.,Bird, N.A.,Twist, K.A.,Halim, H.,Jackson, D.C.,Purcell, A.W.,Turner, S.J.,Doherty, P.C.,Rossjohn, J.,Kedzierska, K. Preemptive priming readily overcomes structure-based mechanisms of virus escape. Proc.Natl.Acad.Sci.USA, 110:5570-5575, 2013 Cited by PubMed: 23493558DOI: 10.1073/pnas.1302935110 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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