4HOT
Crystal Structure of Full-Length Human IFIT5 with 5`-triphosphate Oligoadenine
Summary for 4HOT
Entry DOI | 10.2210/pdb4hot/pdb |
Related | 4HOQ 4HOR 4HOS 4HOU |
Descriptor | Interferon-induced protein with tetratricopeptide repeats 5, RNA (5'-R(*(ATP)P*AP*AP*A)-3'), MAGNESIUM ION, ... (4 entities in total) |
Functional Keywords | tpr, rna binding, antiviral, rna, rna binding protein-rna complex, rna binding protein/rna |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 57389.85 |
Authors | Abbas, Y.M.,Pichlmair, A.,Gorna, M.W.,Superti-Furga, G.,Nagar, B. (deposition date: 2012-10-22, release date: 2013-01-23, Last modification date: 2024-02-28) |
Primary citation | Abbas, Y.M.,Pichlmair, A.,Gorna, M.W.,Superti-Furga, G.,Nagar, B. Structural basis for viral 5'-PPP-RNA recognition by human IFIT proteins. Nature, 494:60-64, 2013 Cited by PubMed: 23334420DOI: 10.1038/nature11783 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.501 Å) |
Structure validation
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