4HCY
Structure of a eukaryotic thiaminase-I bound to the thiamin analogue 3-deazathiamin
Summary for 4HCY
Entry DOI | 10.2210/pdb4hcy/pdb |
Related | 4HCW |
Descriptor | thiaminase-I, 2-{4-[(4-amino-2-methylpyrimidin-5-yl)methyl]-3-methylthiophen-2-yl}ethanol (2 entities in total) |
Functional Keywords | transferase, thiamine pyridinylase |
Biological source | Naegleria gruberi (Amoeba) |
Total number of polymer chains | 6 |
Total formula weight | 237290.81 |
Authors | Kreinbring, C.A.,Hubbard, P.A.,Leeper, F.J.,Hawksley, D.,Petsko, G.A.,Ringe, D. (deposition date: 2012-10-01, release date: 2013-10-02, Last modification date: 2023-09-20) |
Primary citation | Kreinbring, C.A.,Remillard, S.P.,Hubbard, P.,Brodkin, H.R.,Leeper, F.J.,Hawksley, D.,Lai, E.Y.,Fulton, C.,Petsko, G.A.,Ringe, D. Structure of a eukaryotic thiaminase I. Proc.Natl.Acad.Sci.USA, 111:137-142, 2014 Cited by PubMed: 24351929DOI: 10.1073/pnas.1315882110 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.75 Å) |
Structure validation
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