4H5R

HSC70 NBD with Na, Cl and glycerol

Summary for 4H5R

Entry DOI	10.2210/pdb4h5r/pdb
Related	4H5N 4H5T 4H5V 4H5W
Descriptor	Heat shock cognate 71 kDa protein, SODIUM ION, PHOSPHATE ION, ... (7 entities in total)
Functional Keywords	hsc70 nbd domain, transcription
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: P11142
Total number of polymer chains	2
Total formula weight	85769.54
Authors	Stec, B. (deposition date: 2012-09-18, release date: 2014-03-19, Last modification date: 2023-09-20)
Primary citation	Zhang, Z.,Cellitti, J.,Teriete, P.,Pellecchia, M.,Stec, B. New crystal structures of HSC-70 ATP binding domain confirm the role of individual binding pockets and suggest a new method of inhibition. Biochimie, 108:186-192, 2015 Cited by PubMed: 25433210 DOI: 10.1016/j.biochi.2014.11.012 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.64 Å)

Structure validation