4GXS
Ligand binding domain of GluA2 (AMPA/glutamate receptor) bound to (-)-kaitocephalin
Summary for 4GXS
Entry DOI | 10.2210/pdb4gxs/pdb |
Descriptor | Glutamate receptor 2, (5R)-2-[(1S,2R)-2-amino-2-carboxy-1-hydroxyethyl]-5-{(2S)-2-carboxy-2-[(3,5-dichloro-4-hydroxybenzoyl)amino]ethyl}-L-proline, ZINC ION, ... (4 entities in total) |
Functional Keywords | glutamate receptor, glua2, glur2, ampa receptor, neurotransmitter receptor, (-)-kaitocephalin, membrane protein |
Biological source | Rattus norvegicus (brown rat,rat,rats) More |
Cellular location | Cell membrane; Multi-pass membrane protein: P19491 |
Total number of polymer chains | 2 |
Total formula weight | 58855.43 |
Authors | Ahmed, A.H.,Oswald, R.E. (deposition date: 2012-09-04, release date: 2012-10-17, Last modification date: 2023-09-13) |
Primary citation | Ahmed, A.H.,Hamada, M.,Shinada, T.,Ohfune, Y.,Weerasinghe, L.,Garner, P.P.,Oswald, R.E. The structure of (-)-kaitocephalin bound to the ligand binding domain of the (S)-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)/glutamate receptor, GluA2. J.Biol.Chem., 287:41007-41013, 2012 Cited by PubMed: 23076153DOI: 10.1074/jbc.M112.416362 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9634 Å) |
Structure validation
Download full validation report