4GW5

cQYN meditope - Cetuximab Fab

Summary for 4GW5

• Entry DOI: 10.2210/pdb4gw5/pdb
• Related: 4gw1
• Descriptor: Fab Light Chain, Fab Heavy Chain, cQYN meditope, ... (5 entities in total)
• Functional Keywords: igg, immune system, egfr
• Biological source: Mus musculus,Homo sapiens; More
• Total number of polymer chains: 6
• Total formula weight: 97408.95

Authors

Donaldson, J.M.,Zer, C.,Avery, K.N.,Bzymek, K.P.,Horne, D.A.,Williams, J.C. (deposition date: 2012-08-31, release date: 2013-10-09, Last modification date: 2023-09-13)

• Primary citation: Donaldson, J.M.,Zer, C.,Avery, K.N.,Bzymek, K.P.,Horne, D.A.,Williams, J.C.; Identification and grafting of a unique peptide-binding site in the Fab framework of monoclonal antibodies.; Proc.Natl.Acad.Sci.USA, 110:17456-17461, 2013; PubMed: 24101516; DOI: 10.1073/pnas.1307309110

Experimental method

X-RAY DIFFRACTION (2.2 Å)