4GUR
Crystal structure of LSD2-NPAC with H3 in space group P21
Summary for 4GUR
Entry DOI | 10.2210/pdb4gur/pdb |
Related | 4GU1 4GUS 4GUT |
Descriptor | Lysine-specific histone demethylase 1B, Putative oxidoreductase GLYR1, Histone H3.3, ... (7 entities in total) |
Functional Keywords | histone demethylase, oxidoreductase |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus (By similarity): Q8NB78 Nucleus: Q49A26 P84243 |
Total number of polymer chains | 3 |
Total formula weight | 103917.35 |
Authors | |
Primary citation | Fang, R.,Chen, F.,Dong, Z.,Hu, D.,Barbera, A.J.,Clark, E.A.,Fang, J.,Yang, Y.,Mei, P.,Rutenberg, M.,Li, Z.,Zhang, Y.,Xu, Y.,Yang, H.,Wang, P.,Simon, M.D.,Zhou, Q.,Li, J.,Marynick, M.P.,Li, X.,Lu, H.,Kaiser, U.B.,Kingston, R.E.,Xu, Y.,Shi, Y.G. LSD2/KDM1B and its cofactor NPAC/GLYR1 endow a structural and molecular model for regulation of H3K4 demethylation Mol.Cell, 49:558-570, 2013 Cited by PubMed: 23260659DOI: 10.1016/j.molcel.2012.11.019 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.506 Å) |
Structure validation
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