4GUQ
Structure of mutS139F p73 DNA binding domain complexed with 20BP DNA response element
Summary for 4GUQ
Entry DOI | 10.2210/pdb4guq/pdb |
Related | 4g82 4g83 |
Descriptor | DNA (5'-D(P*GP*AP*AP*CP*AP*TP*GP*TP*TP*C)-3'), Tumor protein p73, ZINC ION (3 entities in total) |
Functional Keywords | tumor suppressor, beta-immunoglobulin, transcription factor, transcription-dna complex, transcription/dna |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: O15350 |
Total number of polymer chains | 4 |
Total formula weight | 53890.95 |
Authors | Ethayathulla, A.S.,Nguyen, H.T.,Viadiu, H. (deposition date: 2012-08-29, release date: 2013-08-14, Last modification date: 2023-09-13) |
Primary citation | Ciribilli, Y.,Monti, P.,Bisio, A.,Nguyen, H.T.,Ethayathulla, A.S.,Ramos, A.,Foggetti, G.,Menichini, P.,Menendez, D.,Resnick, M.A.,Viadiu, H.,Fronza, G.,Inga, A. Transactivation specificity is conserved among p53 family proteins and depends on a response element sequence code. Nucleic Acids Res., 41:8637-8653, 2013 Cited by PubMed: 23892287DOI: 10.1093/nar/gkt657 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.7 Å) |
Structure validation
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