4GUJ

1.50 Angstrom Crystal Structure of the Salmonella enterica 3-Dehydroquinate Dehydratase (aroD) in Complex with Shikimate

Summary for 4GUJ

Entry DOI	10.2210/pdb4guj/pdb
Related	4GUF 4GUG 4GUH 4GUI
Descriptor	3-dehydroquinate dehydratase, (3R,4S,5R)-3,4,5-TRIHYDROXYCYCLOHEX-1-ENE-1-CARBOXYLIC ACID, ZINC ION, ... (4 entities in total)
Functional Keywords	structural genomics, niaid, national institute of allergy and infectious diseases, center for structural genomics of infectious diseases, csgid, tim barrel, lyase
Biological source	Salmonella enterica subsp. enterica serovar Typhimurium
Total number of polymer chains	2
Total formula weight	55803.83
Authors	Light, S.H.,Minasov, G.,Duban, M.-E.,Shuvalova, L.,Kwon, K.,Lavie, A.,Anderson, W.F.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2012-08-29, release date: 2012-09-12, Last modification date: 2023-09-13)
Primary citation	Light, S.H.,Antanasijevic, A.,Krishna, S.N.,Caffrey, M.,Anderson, W.F.,Lavie, A. Crystal structures of type I dehydroquinate dehydratase in complex with quinate and shikimate suggest a novel mechanism of schiff base formation. Biochemistry, 53:872-880, 2014 Cited by PubMed: 24437575 DOI: 10.1021/bi4015506 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.5 Å)

Structure validation