4GPZ
Crystal structure of human B type phosphoglycerate mutase H11 phosphorylated form
Summary for 4GPZ
Entry DOI | 10.2210/pdb4gpz/pdb |
Related | 1YFK |
Descriptor | Phosphoglycerate mutase 1, CHLORIDE ION, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... (4 entities in total) |
Functional Keywords | alpha/beta, isomerase, hydrolase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 60418.08 |
Authors | |
Primary citation | Hitosugi, T.,Zhou, L.,Fan, J.,Elf, S.,Zhang, L.,Xie, J.,Wang, Y.,Gu, T.L.,Aleckovic, M.,Leroy, G.,Kang, Y.,Kang, H.B.,Seo, J.H.,Shan, C.,Jin, P.,Gong, W.,Lonial, S.,Arellano, M.L.,Khoury, H.J.,Chen, G.Z.,Shin, D.M.,Khuri, F.R.,Boggon, T.J.,Kang, S.,He, C.,Chen, J. Tyr26 phosphorylation of PGAM1 provides a metabolic advantage to tumours by stabilizing the active conformation. Nat Commun, 4:1790-1790, 2013 Cited by PubMed: 23653202DOI: 10.1038/ncomms2759 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.65 Å) |
Structure validation
Download full validation report