4GMJ

Structure of human NOT1 MIF4G domain co-crystallized with CAF1

Summary for 4GMJ

• Entry DOI: 10.2210/pdb4gmj/pdb
• Related: 2D5R 2P51 4GML
• Descriptor: CCR4-NOT transcription complex subunit 1, CCR4-NOT transcription complex subunit 7, MAGNESIUM ION, ... (6 entities in total)
• Functional Keywords: ccr4-not, mrna decay, deadenylase, transcription, rna binding protein
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm, P-body (By similarity): A5YKK6; Nucleus: Q9UIV1
• Total number of polymer chains: 6
• Total formula weight: 178792.12

Authors

Petit, P.,Weichenrieder, O.,Wohlbold, L.,Izaurralde, E. (deposition date: 2012-08-16, release date: 2012-10-03, Last modification date: 2023-11-08)

• Primary citation: Petit, A.P.,Wohlbold, L.,Bawankar, P.,Huntzinger, E.,Schmidt, S.,Izaurralde, E.,Weichenrieder, O.; The structural basis for the interaction between the CAF1 nuclease and the NOT1 scaffold of the human CCR4-NOT deadenylase complex; Nucleic Acids Res., 40:11058-11072, 2012; PubMed: 22977175; DOI: 10.1093/nar/gks883

Experimental method

X-RAY DIFFRACTION (2.7 Å)