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4GKK

Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a human mitochondrial anticodon stem loop (ASL) of transfer RNA Methionine (TRNAMET) bound to an mRNA with an AUA-codon in the A-site and paromomycin

Summary for 4GKK

Related3T1Y 2KRY 2UUC 
DescriptorPROTEIN/RNA Complex
Functional KeywordsTranslation initiation, 5-formylcytidine, RIBOSOME-ANTIBIOTIC complex,RIBOSOME/ANTIBIOTIC
Biological sourceThermus thermophilus
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Total number of polymer chains23
Total molecular weight777313.32
Authors
Cantara, W.A.,Murphy IV, F.V.,Spears, J.L.,Demirci, H.,Agris, P.F. (deposition date: 2012-08-11, release date: 2013-06-05, modification date: 2013-07-17)
Primary citation
Cantara, W.A.,Murphy, F.V.,Demirci, H.,Agris, P.F.
Expanded use of sense codons is regulated by modified cytidines in tRNA.
Proc.Natl.Acad.Sci.USA, 110:10964-10969, 2013
PubMed: 23781103
DOI: 10.1073/pnas.1222641110
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (3.2 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliersRNA backbone0.23675.1%15.2%4.4%0.50MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolutionDownload full validation report

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105097
entries available on 2014-12-17
00:00 UTC / 09:00 JST