4GGK
Crystal structure of Zucchini from mouse (mZuc / PLD6 / MitoPLD) bound to tungstate
Summary for 4GGK
Entry DOI | 10.2210/pdb4ggk/pdb |
Related | 1BYR 1BYS 4GGJ |
Descriptor | Mitochondrial cardiolipin hydrolase, ZINC ION, TUNGSTATE(VI)ION, ... (4 entities in total) |
Functional Keywords | pirna pathway, protein-rna interactions, pirna biogenesis, rna interference, rnai, hkd motif ccch zinc finger, nuclease, nucleic acid binding, outer mitochondrial membrane, hydrolase |
Biological source | Mus musculus (mouse) |
Cellular location | Mitochondrion outer membrane; Single-pass membrane protein: Q5SWZ9 |
Total number of polymer chains | 1 |
Total formula weight | 22656.08 |
Authors | Ipsaro, J.J.,Haase, A.D.,Hannon, G.J.,Joshua-Tor, L. (deposition date: 2012-08-06, release date: 2012-10-10, Last modification date: 2023-09-13) |
Primary citation | Ipsaro, J.J.,Haase, A.D.,Knott, S.R.,Joshua-Tor, L.,Hannon, G.J. The structural biochemistry of Zucchini implicates it as a nuclease in piRNA biogenesis. Nature, 491:279-283, 2012 Cited by PubMed: 23064227DOI: 10.1038/nature11502 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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