4GAG
Structure of the broadly neutralizing antibody AP33 in complex with its HCV epitope (E2 residues 412-423)
Summary for 4GAG
Entry DOI | 10.2210/pdb4gag/pdb |
Related | 4GAJ 4GAY |
Descriptor | NEUTRALIZING ANTIBODY AP33 HEAVY CHAIN, NEUTRALIZING ANTIBODY AP33 LIGHT CHAIN, Genome polyprotein, ... (5 entities in total) |
Functional Keywords | antibody fab, neutralizing antibody, hcv e2 binding, immune system |
Biological source | Mus musculus More |
Total number of polymer chains | 3 |
Total formula weight | 49149.42 |
Authors | Potter, J.A.,Owsianka, A.,Angus, A.G.N.,Jeffery, N.,Matthews, D.,Keck, Z.,Lau, P.,Foung, S.K.H.,Taylor, G.L.,Patel, A.H. (deposition date: 2012-07-25, release date: 2012-10-10, Last modification date: 2019-12-25) |
Primary citation | Potter, J.A.,Owsianka, A.M.,Jeffery, N.,Matthews, D.J.,Keck, Z.Y.,Lau, P.,Foung, S.K.,Taylor, G.L.,Patel, A.H. Toward a Hepatitis C Virus Vaccine: the Structural Basis of Hepatitis C Virus Neutralization by AP33, a Broadly Neutralizing Antibody. J.Virol., 86:12923-12932, 2012 Cited by PubMed: 22993159DOI: 10.1128/JVI.02052-12 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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