4FZF
Crystal structure of MST4-MO25 complex with DKI
Summary for 4FZF
Entry DOI | 10.2210/pdb4fzf/pdb |
Related | 4FZA 4FZD |
Descriptor | Calcium-binding protein 39, Serine/threonine-protein kinase MST4, 5-AMINO-3-{[4-(AMINOSULFONYL)PHENYL]AMINO}-N-(2,6-DIFLUOROPHENYL)-1H-1,2,4-TRIAZOLE-1-CARBOTHIOAMIDE (3 entities in total) |
Functional Keywords | scaffold protein, protein ser/thr kinase, atp binding, signaling protein-transferase-inhibitor complex, signaling protein/transferase/inhibitor |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm (Potential): Q9Y376 Cytoplasm: Q9P289 |
Total number of polymer chains | 2 |
Total formula weight | 70667.20 |
Authors | Shi, Z.B.,Zhou, Z.C. (deposition date: 2012-07-06, release date: 2013-03-06, Last modification date: 2023-11-08) |
Primary citation | Shi, Z.,Jiao, S.,Zhang, Z.,Ma, M.,Zhang, Z.,Chen, C.,Wang, K.,Wang, H.,Wang, W.,Zhang, L.,Zhao, Y.,Zhou, Z. Structure of the MST4 in Complex with MO25 Provides Insights into Its Activation Mechanism Structure, 21:449-461, 2013 Cited by PubMed: 23434407DOI: 10.1016/j.str.2013.01.007 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.64 Å) |
Structure validation
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