4FQX

Crystal structure of HLA-DM bound to HLA-DR1

Summary for 4FQX

• Entry DOI: 10.2210/pdb4fqx/pdb
• Descriptor: HLA class II histocompatibility antigen, DM alpha chain, HLA class II histocompatibility antigen, DM beta chain, Synthetic peptide, ... (7 entities in total)
• Functional Keywords: immune complex, peptide loading, peptide editing, antigen presentation, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 5
• Total formula weight: 92704.32

Authors

Sethi, D.K.,Pos, W.,Wucherpfennig, K.W. (deposition date: 2012-06-25, release date: 2013-01-09, Last modification date: 2020-07-29)

• Primary citation: Pos, W.,Sethi, D.K.,Call, M.J.,Schulze, M.S.,Anders, A.K.,Pyrdol, J.,Wucherpfennig, K.W.; Crystal Structure of the HLA-DM-HLA-DR1 Complex Defines Mechanisms for Rapid Peptide Selection.; Cell(Cambridge,Mass.), 151:1557-1568, 2012; PubMed: 23260142; DOI: 10.1016/j.cell.2012.11.025

Experimental method

X-RAY DIFFRACTION (2.599 Å)