4FQN
Crystal structure of the CCM2 C-terminal Harmonin Homology Domain (HHD)
Summary for 4FQN
| Entry DOI | 10.2210/pdb4fqn/pdb |
| Descriptor | Malcavernin (2 entities in total) |
| Functional Keywords | helical domain, harmonin-homology domain, protein-protein interaction, homo-dimer, protein binding |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm (By similarity): Q9BSQ5 |
| Total number of polymer chains | 4 |
| Total formula weight | 44650.40 |
| Authors | Fisher, O.S.,Zhang, R.,Li, X.,Murphy, J.W.,Boggon, T.J. (deposition date: 2012-06-25, release date: 2012-12-19, Last modification date: 2024-02-28) |
| Primary citation | Fisher, O.S.,Zhang, R.,Li, X.,Murphy, J.W.,Demeler, B.,Boggon, T.J. Structural studies of cerebral cavernous malformations 2 (CCM2) reveal a folded helical domain at its C-terminus. Febs Lett., 587:272-277, 2013 Cited by PubMed: 23266514DOI: 10.1016/j.febslet.2012.12.011 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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