4FLM
S-formylglutathione Hydrolase W197I Variant containing Copper
Summary for 4FLM
| Entry DOI | 10.2210/pdb4flm/pdb |
| Related | 1PV1 3C6B 4FOL |
| Descriptor | S-formylglutathione hydrolase, COPPER (II) ION (3 entities in total) |
| Functional Keywords | oxidation sensor motif, esterase activity activation, esterase activity inhibition, cysteine sulfinic acid, cys-60, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
| Biological source | Saccharomyces cerevisiae (yeast) |
| Cellular location | Cytoplasm: P40363 |
| Total number of polymer chains | 2 |
| Total formula weight | 68271.45 |
| Authors | Legler, P.M.,Millard, C.B. (deposition date: 2012-06-14, release date: 2012-09-05, Last modification date: 2023-09-13) |
| Primary citation | Legler, P.M.,Leary, D.H.,Hervey, W.J.,Millard, C.B. A role for His-160 in peroxide inhibition of S. cerevisiae S-formylglutathione hydrolase: Evidence for an oxidation sensitive motif. Arch.Biochem.Biophys., 528:7-20, 2012 Cited by PubMed: 22906720DOI: 10.1016/j.abb.2012.08.001 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.41 Å) |
Structure validation
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