4FLA

Crystal structure of human RPRD1B, carboxy-terminal domain

Summary for 4FLA

Entry DOI	10.2210/pdb4fla/pdb
Descriptor	Regulation of nuclear pre-mRNA domain-containing protein 1B, UNKNOWN ATOM OR ION (3 entities in total)
Functional Keywords	structural genomics consortium, sgc, transcription
Biological source	Homo sapiens (human)
Cellular location	Nucleus: Q9NQG5
Total number of polymer chains	4
Total formula weight	69462.70
Authors	Ni, Z.,Xu, C.,Tempel, W.,El Bakkouri, M.,Loppnau, P.,Guo, X.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.M.,Min, J.,Greenblatt, J.F.,Structural Genomics Consortium (SGC) (deposition date: 2012-06-14, release date: 2012-08-22, Last modification date: 2024-02-28)
Primary citation	Ni, Z.,Xu, C.,Guo, X.,Hunter, G.O.,Kuznetsova, O.V.,Tempel, W.,Marcon, E.,Zhong, G.,Guo, H.,Kuo, W.H.,Li, J.,Young, P.,Olsen, J.B.,Wan, C.,Loppnau, P.,El Bakkouri, M.,Senisterra, G.A.,He, H.,Huang, H.,Sidhu, S.S.,Emili, A.,Murphy, S.,Mosley, A.L.,Arrowsmith, C.H.,Min, J.,Greenblatt, J.F. RPRD1A and RPRD1B are human RNA polymerase II C-terminal domain scaffolds for Ser5 dephosphorylation. Nat.Struct.Mol.Biol., 21:686-695, 2014 Cited by PubMed: 24997600 DOI: 10.1038/nsmb.2853 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation