4FHQ

Crystal Structure of HVEM

Summary for 4FHQ

• Entry DOI: 10.2210/pdb4fhq/pdb
• Related: 1JMA 2AW2
• Descriptor: Tumor necrosis factor receptor superfamily member 14 (2 entities in total)
• Functional Keywords: cysteine rich domain, tnf receptor, structural genomics, psi-biology, protein structure initiative, atoms-to-animals: the immune function network, ifn, tnfrsf, cysteine rich domains, receptor, tnf14, btla, cd160, gd of hsv, membrane, new york structural genomics research consortium (nysgrc), immune system
• Biological source: Homo sapiens (human)
• Cellular location: Membrane ; Single-pass type I membrane protein : Q92956
• Total number of polymer chains: 1
• Total formula weight: 14332.18

Authors

Liu, W.,Zhan, C.,Patskovsky, Y.,Bhosle, R.C.,Nathenson, S.G.,Almo, S.C.,Atoms-to-Animals: The Immune Function Network (IFN),New York Structural Genomics Research Consortium (NYSGRC) (deposition date: 2012-06-06, release date: 2012-07-18, Last modification date: 2023-09-13)

• Primary citation: Liu, W.,Vigdorovich, V.,Zhan, C.,Patskovsky, Y.,Bonanno, J.B.,Nathenson, S.G.,Almo, S.C.; Increased Heterologous Protein Expression in Drosophila S2 Cells for Massive Production of Immune Ligands/Receptors and Structural Analysis of Human HVEM.; Mol Biotechnol, 57:914-922, 2015; PubMed: 26202493; DOI: 10.1007/s12033-015-9881-2

Experimental method

X-RAY DIFFRACTION (2.251 Å)