4FH0
Crystal Structure of Human BinCARD CARD, double mutant F16M/L66M SeMet form
Summary for 4FH0
Entry DOI | 10.2210/pdb4fh0/pdb |
Related | 4DWN |
Descriptor | Bcl10-interacting CARD protein, SULFATE ION (3 entities in total) |
Functional Keywords | immune system, apoptosis, mainly alpha, bcl10, nucleus, er, mitochondria |
Biological source | Homo sapiens (human) |
Cellular location | Isoform 1: Nucleus . Isoform 2: Endoplasmic reticulum membrane ; Single-pass membrane protein : Q96LW7 |
Total number of polymer chains | 2 |
Total formula weight | 24559.17 |
Authors | Chen, K.-E.,Kobe, B.,Martin, J.L. (deposition date: 2012-06-05, release date: 2013-02-06, Last modification date: 2018-01-24) |
Primary citation | Chen, K.E.,Richards, A.A.,Caradoc-Davies, T.T.,Vajjhala, P.R.,Robin, G.,Lua, L.H.,Hill, J.M.,Schroder, K.,Sweet, M.J.,Kellie, S.,Kobe, B.,Martin, J. The structure of the caspase recruitment domain of BinCARD reveals that all three cysteines can be oxidized. Acta Crystallogr.,Sect.D, 69:774-784, 2013 Cited by PubMed: 23633586DOI: 10.1107/S0907444913001558 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.4 Å) |
Structure validation
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