4F7S
Crystal structure of human CDK8/CYCC in the DMG-in conformation
Summary for 4F7S
Entry DOI | 10.2210/pdb4f7s/pdb |
Related | 4G6L |
Descriptor | Cyclin-dependent kinase 8, Cyclin-C, N-(2-phenylethyl)quinazolin-4-amine, ... (6 entities in total) |
Functional Keywords | protein kinase complex, proteros, transferase-transcription-inhibitor complex, transferase/transcription/inhibitor |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus : P49336 P24863 |
Total number of polymer chains | 2 |
Total formula weight | 81803.15 |
Authors | Schneider, E.V.,Boettcher, J.,Huber, R.,Maskos, K. (deposition date: 2012-05-16, release date: 2013-05-01, Last modification date: 2023-09-13) |
Primary citation | Schneider, E.V.,Bottcher, J.,Huber, R.,Maskos, K.,Neumann, L. Structure-kinetic relationship study of CDK8/CycC specific compounds. Proc.Natl.Acad.Sci.USA, 110:8081-8086, 2013 Cited by PubMed: 23630251DOI: 10.1073/pnas.1305378110 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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