4F6H
Mutagenesis of zinc ligand residue Cys221 reveals plasticity in the IMP-1 metallo-b-lactamase active site
Summary for 4F6H
Entry DOI | 10.2210/pdb4f6h/pdb |
Related | 4F6Z |
Descriptor | Beta-lactamase, ZINC ION, PHOSPHATE ION, ... (5 entities in total) |
Functional Keywords | metallo-b-lactamase, b-lactamase, hydrolase |
Biological source | Pseudomonas aeruginosa |
Total number of polymer chains | 1 |
Total formula weight | 26590.21 |
Authors | Horton, L.B.,Shanker, S.,Sankaran, B.,Mikulski, R.,Brown, N.G.,Phillips, K.,Lykissa, E.,Prasad, B.V.V.,Palzkill, T.G. (deposition date: 2012-05-14, release date: 2013-03-27, Last modification date: 2023-09-13) |
Primary citation | Horton, L.B.,Shanker, S.,Mikulski, R.,Brown, N.G.,Phillips, K.J.,Lykissa, E.,Venkataram Prasad, B.V.,Palzkill, T. Mutagenesis of zinc ligand residue Cys221 reveals plasticity in the IMP-1 metallo-beta-lactamase active site Antimicrob.Agents Chemother., 56:5667-5677, 2012 Cited by PubMed: 22908171DOI: 10.1128/AAC.01276-12 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.744 Å) |
Structure validation
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