4F52
Structure of a Glomulin-RBX1-CUL1 complex
Summary for 4F52
Entry DOI | 10.2210/pdb4f52/pdb |
Descriptor | Cullin-1, E3 ubiquitin-protein ligase RBX1, Glomulin, ... (4 entities in total) |
Functional Keywords | cullin-ring e3 ligase, inhibitor, cell cycle-ligase-signaling protein complex, cell cycle/ligase/signaling protein |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm: P62877 |
Total number of polymer chains | 6 |
Total formula weight | 226362.20 |
Authors | Duda, D.M.,Olszewski, J.L.,Schulman, B.A. (deposition date: 2012-05-11, release date: 2012-09-19, Last modification date: 2024-02-28) |
Primary citation | Duda, D.M.,Olszewski, J.L.,Tron, A.E.,Hammel, M.,Lambert, L.J.,Waddell, M.B.,Mittag, T.,Decaprio, J.A.,Schulman, B.A. Structure of a Glomulin-RBX1-CUL1 Complex: Inhibition of a RING E3 Ligase through Masking of Its E2-Binding Surface. Mol.Cell, 47:371-382, 2012 Cited by PubMed: 22748924DOI: 10.1016/j.molcel.2012.05.044 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
Download full validation report