4F11

Crystal structure of the extracellular domain of human GABA(B) receptor GBR2

Summary for 4F11

Entry DOI	10.2210/pdb4f11/pdb
Descriptor	Gamma-aminobutyric acid type B receptor subunit 2 (2 entities in total)
Functional Keywords	venus flytrap module, g-protein coupled receptor, signaling protein
Biological source	Homo sapiens (human)
Cellular location	Cell membrane; Multi-pass membrane protein: O75899
Total number of polymer chains	1
Total formula weight	49127.49
Authors	Geng, Y.,Xiong, D.,Mosyak, L.,Malito, D.L.,Kniazeff, J.,Chen, Y.,Burmakina, S.,Quick, M.,Bush, M.,Javitch, J.A.,Pin, J.-P.,Fan, Q.R. (deposition date: 2012-05-05, release date: 2012-06-06, Last modification date: 2012-08-15)
Primary citation	Geng, Y.,Xiong, D.,Mosyak, L.,Malito, D.L.,Kniazeff, J.,Chen, Y.,Burmakina, S.,Quick, M.,Bush, M.,Javitch, J.A.,Pin, J.P.,Fan, Q.R. Structure and functional interaction of the extracellular domain of human GABA(B) receptor GBR2. Nat.Neurosci., 15:970-978, 2012 Cited by PubMed: 22660477 DOI: 10.1038/nn.3133 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.38 Å)

Structure validation