4EO7
Crystal structure of the TIR domain of human myeloid differentiation primary response protein 88.
Summary for 4EO7
| Entry DOI | 10.2210/pdb4eo7/pdb |
| Related | 4DOM |
| Descriptor | Myeloid differentiation primary response protein MyD88, MAGNESIUM ION (3 entities in total) |
| Functional Keywords | adapter protein, toll like receptor, beta-alpha-beta fold, parallel beta sheet, tir-domain, innate immune signaling, signaling protein, tirap/mal, protein binding |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm: Q99836 |
| Total number of polymer chains | 1 |
| Total formula weight | 16804.93 |
| Authors | Snyder, G.A.,Cirl, C.,Jiang, J.S.,Chen, P.,Smith, T.,Xiao, T.S. (deposition date: 2012-04-13, release date: 2013-04-10, Last modification date: 2023-12-06) |
| Primary citation | Snyder, G.A.,Cirl, C.,Jiang, J.,Chen, K.,Waldhuber, A.,Smith, P.,Rommler, F.,Snyder, N.,Fresquez, T.,Durr, S.,Tjandra, N.,Miethke, T.,Xiao, T.S. Molecular mechanisms for the subversion of MyD88 signaling by TcpC from virulent uropathogenic Escherichia coli. Proc.Natl.Acad.Sci.USA, 110:6985-6990, 2013 Cited by PubMed: 23569230DOI: 10.1073/pnas.1215770110 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.449 Å) |
Structure validation
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