4EIH
Crystal structure of Arg SH2 domain
Summary for 4EIH
Entry DOI | 10.2210/pdb4eih/pdb |
Descriptor | Abelson tyrosine-protein kinase 2, CHLORIDE ION (3 entities in total) |
Functional Keywords | sh2 domain, protein/protein interaction, phosphotyrosine, phosphopeptide, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm, cytoskeleton: P42684 |
Total number of polymer chains | 1 |
Total formula weight | 12798.75 |
Authors | Liu, W.,MacGrath, S.M.,Koleske, A.J.,Boggon, T.J. (deposition date: 2012-04-05, release date: 2013-04-10, Last modification date: 2023-09-13) |
Primary citation | Gifford, S.M.,Liu, W.,Mader, C.C.,Halo, T.L.,Machida, K.,Boggon, T.J.,Koleske, A.J. Two Amino Acid Residues Confer Different Binding Affinities of Abelson Family Kinase Src Homology 2 Domains for Phosphorylated Cortactin. J.Biol.Chem., 289:19704-19713, 2014 Cited by PubMed: 24891505DOI: 10.1074/jbc.M114.556480 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.2 Å) |
Structure validation
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