4EI5

Crystal Structure of XV19 TCR in complex with CD1d-sulfatide C24:1

Summary for 4EI5

• Entry DOI: 10.2210/pdb4ei5/pdb
• Related: 2AKR 4EI6
• Descriptor: Antigen-presenting glycoprotein CD1d1, (15Z)-N-((1S,2R,3E)-2-HYDROXY-1-{[(3-O-SULFO-BETA-D-GALACTOPYRANOSYL)OXY]METHYL}HEPTADEC-3-ENYL)TETRACOS-15-ENAMIDE, Beta-2-microglobulin, ... (10 entities in total)
• Functional Keywords: sulfatide, lipid, cd1d, nkt typeii, tcr, immune system
• Biological source: Mus musculus (mouse); More
• Total number of polymer chains: 8
• Total formula weight: 199821.14

Authors

Patel, O.,Gras, S.,Rossjohn, J. (deposition date: 2012-04-04, release date: 2012-07-25, Last modification date: 2023-09-13)

• Primary citation: Patel, O.,Pellicci, D.G.,Gras, S.,Sandoval-Romero, M.L.,Uldrich, A.P.,Mallevaey, T.,Clarke, A.J.,Le Nours, J.,Theodossis, A.,Cardell, S.L.,Gapin, L.,Godfrey, D.I.,Rossjohn, J.; Recognition of CD1d-sulfatide mediated by a type II natural killer T cell antigen receptor.; Nat.Immunol., 13:857-863, 2012; PubMed: 22820603; DOI: 10.1038/ni.2372

Experimental method

X-RAY DIFFRACTION (3.1 Å)