4E81

Crystal structure of the substrate binding domain of E.coli DnaK in complex with a short apidaecin peptide

Summary for 4E81

Entry DOI	10.2210/pdb4e81/pdb
Related	1DKX 1DKY 1DKZ 3DPO 3DPP 3DPQ 3QNJ
Descriptor	Chaperone protein DnaK, apidaecin peptide fragment, SULFATE ION, ... (4 entities in total)
Functional Keywords	chaperone
Biological source	Escherichia coli More
Cellular location	Cytoplasm : P0A6Y8
Total number of polymer chains	4
Total formula weight	50350.60
Authors	Zahn, M.,Straeter, N. (deposition date: 2012-03-19, release date: 2012-05-30, Last modification date: 2024-02-28)
Primary citation	Czihal, P.,Knappe, D.,Fritsche, S.,Zahn, M.,Berthold, N.,Piantavigna, S.,Muller, U.,Van Dorpe, S.,Herth, N.,Binas, A.,Kohler, G.,De Spiegeleer, B.,Martin, L.L.,Nolte, O.,Strater, N.,Alber, G.,Hoffmann, R. Api88 is a novel antibacterial designer Peptide to treat systemic infections with multidrug-resistant gram-negative pathogens. Acs Chem.Biol., 7:1281-1291, 2012 Cited by PubMed: 22594381 DOI: 10.1021/cb300063v PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation