4DQ2
Structure of staphylococcus aureus biotin protein ligase in complex with biotinol-5'-amp
Summary for 4DQ2
Entry DOI | 10.2210/pdb4dq2/pdb |
Descriptor | Biotin-[acetyl-CoA-carboxylase] ligase, ((2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXY-TETRAHYDROFURAN-2-YL)METHYL 5-((3AS,4S,6AR)-2-OXO-HEXAHYDRO-1H-THIENO[3,4-D]IMIDAZOL-4-YL)PENTYL HYDROGEN PHOSPHATE (3 entities in total) |
Functional Keywords | dna binding domain, metabolism, biotin, ligate, ligase |
Biological source | Staphylococcus aureus |
Total number of polymer chains | 1 |
Total formula weight | 38443.17 |
Authors | Wilce, M.,Yap, M.,Pendini, N.,Soares de Costa, T.,Polyak, S.,Tieu, W.,Booker, G.,Wallace, J. (deposition date: 2012-02-14, release date: 2012-04-18, Last modification date: 2024-03-20) |
Primary citation | Soares da Costa, T.P.,Tieu, W.,Yap, M.Y.,Pendini, N.R.,Polyak, S.W.,Sejer Pedersen, D.,Morona, R.,Turnidge, J.D.,Wallace, J.C.,Wilce, M.C.,Booker, G.W.,Abell, A.D. Selective inhibition of biotin protein ligase from Staphylococcus aureus. J.Biol.Chem., 287:17823-17832, 2012 Cited by PubMed: 22437830DOI: 10.1074/jbc.M112.356576 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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