4DO8

Crystal structure of the muscarinic toxin MT1

Summary for 4DO8

• Entry DOI: 10.2210/pdb4do8/pdb
• Related: 1FF4 2VLW 3FEV 3NEQ
• Descriptor: Muscarinic toxin 1, THIOCYANATE ION, ACETATE ION, ... (4 entities in total)
• Functional Keywords: snake toxin, three-finger toxin fold, muscarinic toxin, muscarinic m1 receptor, neurones, muscarinic m4 receptor, adrenergic receptor, toxin
• Biological source: Dendroaspis angusticeps (Eastern green mamba)
• Cellular location: Secreted: P81030
• Total number of polymer chains: 2
• Total formula weight: 15168.37

Authors

Fruchart-Gaillard, C.,Mournier, G.,Vera, L.,Servent, D.,Stura, E.A. (deposition date: 2012-02-09, release date: 2012-06-27, Last modification date: 2024-04-03)

• Primary citation: Fruchart-Gaillard, C.,Mourier, G.,Blanchet, G.,Vera, L.,Gilles, N.,Menez, R.,Marcon, E.,Stura, E.A.,Servent, D.; Engineering of three-finger fold toxins creates ligands with original pharmacological profiles for muscarinic and adrenergic receptors.; Plos One, 7:e39166-e39166, 2012; PubMed: 22720062; DOI: 10.1371/journal.pone.0039166

Experimental method

X-RAY DIFFRACTION (1.802 Å)