4DN3

Crystal structure of anti-mcp-1 antibody cnto888

Summary for 4DN3

• Entry DOI: 10.2210/pdb4dn3/pdb
• Related: 4DN4
• Descriptor: CNTO888 LIGHT CHAIN, CNTO888 HEAVY CHAIN (3 entities in total)
• Functional Keywords: antibody, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 47316.70

Authors

Obmolova, G.,Teplyakov, A.,Malia, T.,Grygiel, T.,Sweet, R.,Snyder, L.,Gilliland, G. (deposition date: 2012-02-08, release date: 2012-10-03, Last modification date: 2018-01-24)

• Primary citation: Obmolova, G.,Teplyakov, A.,Malia, T.J.,Grygiel, T.L.,Sweet, R.,Snyder, L.A.,Gilliland, G.L.; Structural basis for high selectivity of anti-CCL2 neutralizing antibody CNTO 888.; Mol.Immunol., 51:227-233, 2012; PubMed: 22487721; DOI: 10.1016/j.molimm.2012.03.022

Experimental method

X-RAY DIFFRACTION (2.6 Å)