4DMH

Crystal structure of the CFTR inhibitory factor Cif with the H207A mutation

Summary for 4DMH

Entry DOI	10.2210/pdb4dmh/pdb
Related	3KD2 3KDA 3PI6 4DLN 4DM7 4DMC 4DMF 4DMK 4DNF 4DNO
Descriptor	Putative hydrolase, GLYCEROL (3 entities in total)
Functional Keywords	alpha beta hydrolase, epoxide hydrolase, secreted, hydrolase
Biological source	Pseudomonas aeruginosa
Total number of polymer chains	4
Total formula weight	136758.91
Authors	Bahl, C.D.,Madden, D.R. (deposition date: 2012-02-07, release date: 2013-08-07, Last modification date: 2023-09-13)
Primary citation	Bahl, C.D.,Hvorecny, K.L.,Bomberger, J.M.,Stanton, B.A.,Hammock, B.D.,Morisseau, C.,Madden, D.R. Inhibiting an Epoxide Hydrolase Virulence Factor from Pseudomonas aeruginosa Protects CFTR. Angew.Chem.Int.Ed.Engl., 54:9881-9885, 2015 Cited by PubMed: 26136396 DOI: 10.1002/anie.201503983 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation